Request an Appointment
Upload Image

Regenerative Orthopedics & Orthobiologics

  • Home
  • /
  • Regenerative Orthopedics & Orthobiologics

REGENERATIVE ORTHOPEDICS & ORTHOBIOLOGICS

One Philosophy, Applied Across Every Tissue You Have

Dr. Ceballos Dual Board-Certified Orthopedic Surgeon & Sports Medicine Specialist

Regenerative orthopedics isn’t a single injection or a single product it’s a category of tools I use to support the body’s own capacity to heal, guided by the same surgical judgment I bring to the operating room. PRP, BMAC, stem cell and cellular therapies, and image-guided injection technique are different tools for different problems, chosen based on what your evaluation and imaging actually show, not applied as a one-size-fits-all treatment.

What ties all of it together is precision. Every orthobiologic I use is delivered with image guidance, selected for a specific tissue and a specific diagnosis, and evaluated against the question that matters most: does this genuinely support healing and help preserve your joint, or would your case be better served by a different approach, including surgery. This page is the overview each therapy below has its own dedicated page with the full detail.

Platelet-Rich Plasma (PRP)

PRP concentrates your own blood’s healing factors and delivers them directly to an injured or degenerative area tendon, ligament, muscle, or joint. It’s the most established and broadly applicable orthobiologic I offer, and not all PRP is the same: platelet dose, leukocyte composition, preparation method, and injection accuracy all affect the outcome. Full detail, including how I dose and prepare PRP for different conditions, lives on the dedicated PRP Therapy page.

Bone Marrow Aspirate Concentrate (BMAC)

BMAC is drawn from your own bone marrow typically the pelvis and concentrated to isolate the cellular and growth-factor components most relevant to tissue repair. Because it’s autologous, it carries a different risk and regulatory profile than donor-derived cellular products, and I use it selectively: for joints, tendons, and bone that may benefit from a more concentrated biologic signal than PRP alone provides, and often as an adjunct at the time of surgery.

Stem Cell and Cellular Therapies

For appropriately selected patients, I offer cellular orthobiologic therapy including Wharton’s Jelly-derived mesenchymal stem cells within the specific orthopedic, pain, and wound-care indications Florida law permits. This is a more carefully qualified category than PRP or BMAC: it involves donor-derived tissue, current evidence is still developing, and outcomes cannot be guaranteed. The full explanation of what these products are, where they come from, and how I determine candidacy lives on the dedicated Stem Cell & Cellular Therapies page, along with the required regulatory disclosures.

Intraosseous Orthobiologic Injections

Not all joint pain starts in the joint space it often starts inside the bone. Areas of bone marrow edema or early subchondral bone change, sometimes called bone marrow lesions, are a common and under-treated driver of knee, hip, and shoulder pain, particularly in early-to-moderate osteoarthritis. Intraosseous injection delivers PRP or, in select cases, cellular therapy directly into the subchondral bone under image guidance, rather than into the joint space alone targeting the bone itself as a pain generator, not just the joint around it. This technique is less established than standard intra-articular PRP, appropriate for select patients, and outcomes vary by case.

Biologic Augmentation of Surgery

Orthobiologics aren’t only an alternative to surgery they’re often a part of it. When I perform a repair or reconstruction, PRP or BMAC can be applied directly to the repaired tissue to support the healing environment during the critical early recovery window. This is a decision made case by case, based on what the surgery itself shows, not a routine add-on to every procedure.

Ultrasound- and Fluoroscopic-Guided Injections

Precision of delivery is part of what separates surgical-level regenerative care from a generic injection visit. I don’t perform blind injections. Every orthobiologic I deliver PRP, BMAC, or cellular therapy is placed under ultrasound or, when the target requires it, fluoroscopic guidance, so the material actually reaches the structure it’s meant to treat.

Treatment of Joints, Tendons, Ligaments, Muscles, and Bone

Orthobiologics aren’t limited to one type of tissue. Depending on the diagnosis, I use these tools across the full range of musculoskeletal structures osteoarthritic joints, tendinopathy, ligament injuries, muscle strains and tears, and bone itself in the case of intraosseous treatment and biologic-augmented fracture or nonunion care. The tissue and the diagnosis drive the choice of product and technique, not the other way around.

Who This Is For

  • Patients with joint, tendon, ligament, or muscle injuries who want to explore biologic support before or alongside other treatment
  • Patients with early-to-moderate osteoarthritis looking for options short of joint replacement
  • Patients undergoing surgical repair who want biologic augmentation considered as part of the procedure
  • Patients who have been offered a generic PRP or stem cell injection elsewhere and want a surgeon-directed, image-guided evaluation first

How I Can Help

Because I’m a practicing orthopedic surgeon, the decision of which orthobiologic if any is right for your case isn’t made in isolation from the rest of your orthopedic picture. I can move from direct evaluation, to biologic treatment, to a mechanical or surgical solution if one is genuinely needed, within one relationship, rather than referring you between separate injection clinics and surgical practices that aren’t coordinating with each other.

Important Disclosure

Regenerative orthopedic and orthobiologic therapies referenced on this page are individualized based on a comprehensive orthopedic evaluation. Some therapies, including cellular and stem cell products, are investigational and not FDA-approved for specific orthopedic indications; applicable regulatory disclosures are provided on the relevant treatment pages and in writing before treatment. Individual outcomes vary, and no specific result can be guaranteed. A physician-patient relationship is established only after consultation and informed consent.

Regenerative Orthopedics & Orthobiologics

Frequently Asked Questions

What's the difference between PRP, BMAC, and stem cell therapy?

PRP and BMAC are both derived from your own body PRP from blood, BMAC from bone marrow. Stem cell therapy, as I offer it, typically uses a donor-derived cellular product. Each has a different risk profile, regulatory status, and best-fit indication, and I’ll walk you through which, if any, applies to your case.

How do you decide which orthobiologic to use?

It starts with a precise diagnosis imaging and, when appropriate, direct visualization with needle arthroscopy followed by a discussion of what the evidence actually supports for your specific tissue and condition.

Are these treatments a substitute for surgery?

Sometimes, for appropriately selected patients with earlier-stage disease. For patients with advanced structural damage, they typically aren’t, and I’ll tell you directly where you fall on that spectrum. Orthobiologics can also be used alongside surgery, not only as an alternative to it.

Are stem cell and cellular therapies FDA-approved?

No. These therapies are investigational and not FDA-approved for any specific orthopedic condition. I disclose that directly, along with your other options, before any treatment full detail is on the Stem Cell & Cellular Therapies page.

Do I need imaging before starting any of these treatments?

In almost every case, yes. Treatment is based on a precise diagnosis, not a general request for “a PRP shot” or “a stem cell injection” what’s actually happening in the tissue determines what, if anything, is appropriate.

Schedule an Regenerative Orthopedics Consultation

Scheduling Consultation